The formula examined did reduce facial redness so EUK-134 seems to be tolerated well even by redness-prone, sensitive skin types.Introducing Revita® Hair-Stimulating Shampoo, geared towards individuals troubled by hair loss, thinning hair, and androgenic alopecia (male or female pattern baldness), this high-quality product offers a premium solution. Other than that, we found a study that examined a serum to manage skin redness in sensitive, pale skin types and contained EUK-134 along with a bunch of other ingredients. The protection conferred by EUK-134 results in a significant increase in cell survival following UVB irradiation."Īnother study (also by Estee Lauder) found that EUK-134 lowers hydroperoxide levels at the surface of UVA-exposed skin in vivo and concluded that this salen–manganese compound is a "unique cosmetic tool to protect the skin surface from accumulating oxidative damage". They hypothesize that "EUK-134, via direct protection of the membrane from UVB-induced oxidative damage, reduces oxidative stress induced MAPK signaling and consequently lowers the level of p53 induction. Estee Lauder likes this ingredient, uses it and has done some studies to prove that Ethylbisiminomethylguaiacol Manganese Chloride, aka EUK-134, can nicely protect the cells from UVB damage. So this unpronounceable guy is actually a nice molecule that mimics the behavior of the natural enzymes in our skin. Even though some of its effects are more hyped up than backed up, it is still a nice to have on many ingredient lists. Overall, we think that caffeine is a very versatile and biologically active ingredient. A 2017 study compared a 0.2% caffeine liquid with a 5% Minoxidil (an FDA approved active to treat baldness) solution and found that " a caffeine-based topical liquid should be considered as not inferior to minoxidil 5% solution in men with androgenetic alopecia", or English translation means that the caffeine liquid was pretty much as good as the FDA-approved Minoxidil stuff. We have found some recent and promising research to back this up. The theory is that it can inhibit the activity of the 5-α-reductase enzyme that plays an important role in hair loss and allows a renewed growth phase of the hair. Last, but not least, we have to write about caffeine and hair growth. But here again, the evidence that it actually makes a measurable, let alone visible, improvement on actual human beings is limited (we could find only some animal skin studies or caffeine being combined with other actives). In theory, it can speed up the lipolysis process (the "fat burning" by our cells) and stimulate the draining lymph system that might lead to the improvement of cellulite. Though conventional wisdom and anecdotal evidence says that this property is helpful for dark under-eye circles and puffy eyes, we have to mention that the double-blind research we have found about a 3% caffeine gel concluded that " the overall efficacy of the selected caffeine gel in reducing puffy eyes was not significantly different from that of its gel base." But you know, the proof is in the pudding.Īnother thing Caffeine is used for in body care products is its anti-cellulite effects. Ethylbisiminomethylguaiacol Manganese Chloride ,Įthylbisiminomethylguaiacol Manganese ChlorideĪ well-known thing about Caffeine is that it improves the microcirculation of the blood vessels.
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